READING, Pa. (AP) — Conjoined twins Lori and George Schappell, who pursued separate careers, interests and relationships during lives that defied medical expectations, died this month in Pennsylvania, according to funeral home officials. They were 62.

The twins, listed by Guinness World Records as the oldest living conjoined twins, died April 7 at the Hospital of the University of Pennsylvania, according to obituaries posted by Leibensperger Funeral Homes of Hamburg. The cause of death was not detailed.

“When we were born, the doctors didn’t think we’d make 30, but we proved them wrong,” Lori said in an interview when they turned 50, The Philadelphia Inquirer reported. George came out as transgender in 2007.

The twins, born Sept. 18, 1961, in West Reading, Pennsylvania, had distinct brains but were joined at the skull. George, who had spina bifida and was 4 inches shorter, was wheeled around by Lori on an adaptive wheeled stool. Despite each having to go where the other went, it was “very important” to both “to live as independently as possible,” the obituary said.